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Table 1 Calculation of the ALDEN score for each drug administrated during the hospitalization (chronic treatments were excluded) [10]

From: A case report of toxic epidermal necrolysis (TEN) in a patient with COVID-19 treated with hydroxychloroquine: are these two partners in crime?

DRUG ALDEN score Causal link
Enoxaparin −2 Very unlikelya
Oseltamivir −2 Very unlikely
Ceftriaxone +1 Unlikely
Potassium Canrenoate −3 Very unlikely
Pantoprazole −2 Very unlikelya
Hydroxychloroquine +4 Possible
Piperacillin/Tazobactam +1 Unlikely
Dexamethasone 0 Unlikely
Levofloxacin +1 Unlikely
Paracetamol −1 Very unlikelya
  1.  < 0: very unlikely
  2. 0–1: unlikely
  3. 2–3: possible
  4. 4–5: probable
  5.  ≥ 6: very probable
  6. are-challenge without any adverse reactions. Score (−12; +10)