Table 1 Comparison between the laboratory findings in the two MDA5+ patients with dermatomyositis
From: MDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentations
| Patient #1 | Patient #2 | Reference values | |
|---|---|---|---|
| Total blood counts | |||
| WBC | 1.67 | 5.17 | 4–10 × 109/L |
| Neutrophils | 1.08 | 1.66 | 1.5–7.5 × 109/L |
| Lymphocytes | 0.27 | 2.67 | 1–5 × 109/L |
| Hb | 9.8 | 12.8 | 13–16 g/dL |
| PLTs | 130 | 217 | 140–440 × 109/L |
| Liver enzymes | |||
| AST | 244 | 28 | 15–37 U/L |
| ALT | 263 | 48 | 12–65 U/L |
| Cholestasis indexes | |||
| ɣ-GT | 399 | 117 | 5–85 U/L |
| AP | 120 | 92 | 50–136 U/L |
| Total bilirubin | 0.7 | 0.5 | 0.2–1 mg/dL |
| Muscle enzymes | |||
| LDH | 483 | 255 | 84–246 U/L |
| CPK | 662 | 28 | 35–232 U/L |
| Aldolase | 11.2 | 7.4 | <7.3 U/mL |
| Indexes of inflammation | |||
| ESR | 50 | 41 | 2–10 mm/h |
| CRP | <9 | <9 | <9 mg/L |
| Ferritin | 4218 | 292 | 26–388 ng/mL |
| Autoantibodies | |||
| ANA | 1/640 | Neg | <1/80 |
| Anti-MDA5 | +++ (72) | +++ (58) | Neg |
| Anti-Ro52 | +++ (84) | Neg | Neg |