Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

Table 4 Adjusted¹⁾ association of IL6(-174G>C) and IL18(-137G>C) with hay fever²⁾ in the SAPALDIA Cohort Study.

1) Adjusted for age and gender. ²⁾ Self-reported hay fever cases answered yes to 'Have you ever had a problem with sneezing or a runny nose or a blocked nose when you did not have a cold?', irrespective of self-reported asthma or eczema. ³⁾ Non-atopic controls were free of self-reported hay fever, self-reported eczema and physician-diagnosed asthma. ⁴⁾ Controls had total IgE ≤ 100 kU/L or were negative for all specific allergen tested (Phadiatop).

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