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ECRHS-Basel N = 418 (%)
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SAPALDIA N = 6003 (%)
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Female proportion
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211 (50.5)
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3022 (50.3)
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Age [years]
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43.4 (± 7.0)
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41.3 (± 11.4)
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Age range [years]
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29.3 to 55.1
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18.2 to 61.8
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Hay fever cases2)
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192 (45.9)
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1105 (18.4)
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Asthma cases3)
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78 (18.2)
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369 (6.2)
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Eczema cases4)
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200 (47.9)
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2383 (39.7)
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Elevated total IgE cases5)
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101 (24.9)
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1168 (21.6)
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Allergen sensitization cases6)
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178 (42.6)
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1620 (29.1)
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Non-atopic controls7)
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125 (29.9)
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2953 (49.2)
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- 1) Presented in N (%) for categorical and in mean (± SD) for continuous variables.
- 2) Self-reported hay fever cases answered yes to, Have you ever had a problem with sneezing or a runny nose or a blocked nose when you did not have a cold?', irrespective of self-reported asthma or eczema.
- 3) Physician-diagnosed asthma cases answered twice yes to 'Have you ever had asthma? Was this confirmed by a doctor?', irrespective of self-reported hay fever or eczema.
- 4) Self-reported eczema cases answered yes to 'Have you ever had eczema or any other kind of skin allergy?', irrespective of self-reported asthma or hay fever.
- 5) Elevated total IgE cases had serum total IgE level >100 kU/L, measured by CAP system (Pharmacia)
- 6) Allergen sensitization cases had at least one allergen specific IgE >0.35 kU/L, measured by CAP system (Pharmacia) for ECRHS-BS and by Phadiatop test (CAP FEIA system, Pharmacia) for SAPALDIA.
- 7) Non-atopic controls were free of self-reported hay fever, self-reported eczema and physician-diagnosed asthma.