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Disease classification
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No asthma
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Intermittent
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Mild persistent
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Moderate/severe persistent
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p value
|
|---|
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Number of subjects
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93
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31
|
15
|
20
| |
|
Age(years) (±SD)
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7.6 ± 0.8
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7.6 ± 0.5
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7.4 ± 0.8
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7.4 ± 1.0
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0.54
|
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Female
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46 (49%)
|
10 (32%)
|
6 (40%)
|
8 (40%)
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0.38
|
|
Male
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47 (51%)
|
21 (68%)
|
9 (60%)
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12 (60%)
| |
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Caucasian
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89 (96%)
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29 (94%)
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11 (73%)
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16 (80)
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0.008
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African American
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3 (3%)
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3 (10%)
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6 (40%)
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6 (30%)
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<0.0001
|
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American Indian
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4 (4%)
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0 (0%)
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0 (0%)
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0 (0%)
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0.84
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Asian
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0 (0%)
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1 (3%)
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0 (0%)
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0 (0%)
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0.42
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Hispanic or Latino
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4 (4 %)
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1 (3%)
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1 (7%)
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0 (0%)
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0.83
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Spirometry(median [25th, 75th])
| | | | | |
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FEV1
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1.50 [1.37, 1.72]
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1.54 [1.27, 1.66]
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1.23 [1.09, 1.63]
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1.46 [1.29, 1.83]
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0.11
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FEV1% pred
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103 [95, 109]
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103 [89, 113]
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90 [85, 101]
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102 [94, 107]
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0.43
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FVC
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1.85 [1.64, 2.06]
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1.81 [1.60, 2.05]
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1.62 [1.31, 1.93]
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1.88 [1.51, 2.21]
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0.06
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FVC% pred
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108 [100, 115]
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110 [98, 118]
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96 [94, 116]
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114 [105, 120]
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0.19
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|
FEV0.5
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1.11 [1.01, 1.30]
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1.14 [0.97, 1.29]
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0.92 [0.78, 1.18]
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1.07 [0.97, 1.21]
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0.07
|
|
FEF25-75
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1.63 [1.23, 1.95]
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1.54 [1.03, 1.88]
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1.21 [0.98, 1.51]
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1.48 [1.25, 1.70]
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0.16
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PEF
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2.98 [2.58, 3.50]
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3.20 [2.59, 3.65]
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2.46 [2.16, 2.99]
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2.66 [2.51, 3.17]
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0.07
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FEV1/FVC
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0.85 [0.79, 0.88]
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0.82 [0.77, 0.86]
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0.82 [0.81, 0.88]
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0.81 [0.77, 0.86]
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0.43
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FEV0.5/FVC
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0.63 [0.58, 0.69]
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0.60 [0.55, 0.65]
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0.62 [0.56, 0.65]
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0.57 [0.55, 0.65]
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0.24
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Total lgE (median [25th, 75th])
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38 [19, 92]
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49 [15, 103]
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149 [20, 331]
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218 [103, 475]
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0.001
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Any FEIA
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40/91 (44%)
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16/29 (55%)
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11/15 (73%)
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17/20 (85%)
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0.003
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Aero FEIA
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38/91 (42%)
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16/29 (55%)
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11/15 (73%)
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17/20 (85%)
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0.002
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Perennial aero FEIA
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34/91 (37%)
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15/29 (52%)
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11/15 (73%)
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16/20 (80%)
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0.001
|
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Seasonal aero FEIA
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23/91 (25%)
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7/29 (24%)
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4/15 (27%)
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9/20 (45%)
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0.33
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- FEV1 Forced Expiratory Volume at 1 second, FEV1%pred FEV1 percent predicted, FVC forced vital capacity, FVC%pred, FVC percent predicted; FEV0.5, Forced Expiratory Volume at 0.5 second, FEF25-75, Forced expiratory flow at 25% to 75% of FVC; PEF, peak expiratory flow rate; Aero FEIA, aeroallergen fluoroenzyme immunoassay.
